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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDC All Species: 25.76
Human Site: T18 Identified Species: 51.52
UniProt: P20941 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P20941 NP_002588.3 246 28246 T18 E D F E G Q A T H T G P K G V
Chimpanzee Pan troglodytes XP_524997 413 46384 T185 E D F E G Q A T H T G P K G V
Rhesus Macaque Macaca mulatta XP_001107723 274 31485 T46 E D F E G Q A T H T G P K G V
Dog Lupus familis XP_852231 301 34185 V55 L A G E G I S V N T G P K G V
Cat Felis silvestris
Mouse Mus musculus Q9QW08 244 27998 T18 E D F E G Q A T H T G P K G V
Rat Rattus norvegicus P20942 246 28111 T18 E D F E G Q A T H T G P K G V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516854 245 28140 T18 E D F E G Q A T H T G P K G V
Chicken Gallus gallus XP_426634 247 28345 G19 Q T L S I R T G P K G V I N D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_682823 236 27114 A12 P E I E E L P A T Q T G P K G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VUR7 276 30957 S18 E K L E Y Y C S S S E G E D N
Honey Bee Apis mellifera XP_393706 284 32413 E38 S D K E T E D E K Y P Q I I T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_799253 293 33509 S44 Q N K D C A A S P E A E F I P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 59 87.9 40.5 N.A. 88.2 87.8 N.A. 73.5 72 N.A. 61.7 N.A. 28.9 30.2 N.A. 30
Protein Similarity: 100 59.3 89 61.4 N.A. 95.1 94.7 N.A. 86.5 85 N.A. 79.2 N.A. 50 50.3 N.A. 50.1
P-Site Identity: 100 100 100 53.3 N.A. 100 100 N.A. 100 6.6 N.A. 6.6 N.A. 13.3 13.3 N.A. 6.6
P-Site Similarity: 100 100 100 66.6 N.A. 100 100 N.A. 100 20 N.A. 13.3 N.A. 33.3 20 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 0 9 59 9 0 0 9 0 0 0 0 % A
% Cys: 0 0 0 0 9 0 9 0 0 0 0 0 0 0 0 % C
% Asp: 0 59 0 9 0 0 9 0 0 0 0 0 0 9 9 % D
% Glu: 59 9 0 84 9 9 0 9 0 9 9 9 9 0 0 % E
% Phe: 0 0 50 0 0 0 0 0 0 0 0 0 9 0 0 % F
% Gly: 0 0 9 0 59 0 0 9 0 0 67 17 0 59 9 % G
% His: 0 0 0 0 0 0 0 0 50 0 0 0 0 0 0 % H
% Ile: 0 0 9 0 9 9 0 0 0 0 0 0 17 17 0 % I
% Lys: 0 9 17 0 0 0 0 0 9 9 0 0 59 9 0 % K
% Leu: 9 0 17 0 0 9 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 9 0 0 0 0 0 0 9 0 0 0 0 9 9 % N
% Pro: 9 0 0 0 0 0 9 0 17 0 9 59 9 0 9 % P
% Gln: 17 0 0 0 0 50 0 0 0 9 0 9 0 0 0 % Q
% Arg: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % R
% Ser: 9 0 0 9 0 0 9 17 9 9 0 0 0 0 0 % S
% Thr: 0 9 0 0 9 0 9 50 9 59 9 0 0 0 9 % T
% Val: 0 0 0 0 0 0 0 9 0 0 0 9 0 0 59 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 9 9 0 0 0 9 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _